Nigerian Journal of Surgery

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 27  |  Issue : 1  |  Page : 5--8

The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial


Sudhir Kumar Jain, Tariq Hameed, Dhruv Jain, Mohak Singh, Adiba Nizam 
 Department of Surgery, Maulana Azad Medical College, New Delhi, India

Correspondence Address:
Dr. Tariq Hameed
Department of Surgery, Maulana Azad Medical College, New Delhi
India

Objective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the placebo group and antibiotic group, a total of 150 patients were enrolled in the study. Follow-up was done up to 1 month to look for any evidence of surgical site infection using the criteria of Centers for Disease Control on wound infection. Results: Twelve patients in the antibiotic group and nine patients in the placebo group were found to have evidence of surgical site infection. This difference was found to be insignificant with P = 0.14. Three patients in the placebo group developed deep surgical site infection but on analysis, this difference was also found to be insignificant with P = 0.122.None of these patients required mesh removal. Conclusion: The result of the present study suggests that the use of prophylactic antibiotics during mesh repair of primary inguinal hernias does not give any extra protection from infections. Multicenter meta-analysis is required to give definite guidelines regarding the use of prophylactic antibiotics.


How to cite this article:
Jain SK, Hameed T, Jain D, Singh M, Nizam A. The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial.Niger J Surg 2021;27:5-8


How to cite this URL:
Jain SK, Hameed T, Jain D, Singh M, Nizam A. The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial. Niger J Surg [serial online] 2021 [cited 2023 Mar 25 ];27:5-8
Available from: https://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jain;type=0