Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page Small font size Default font size Increase font size Users Online: 450


 
  Table of Contents  
CASE REPORT
Year : 2021  |  Volume : 27  |  Issue : 1  |  Page : 75-77  

Giant schwannoma on thenar aspect of the hand: A rare case report


Department of General Surgery, RIMS, Ranchi, Jharkhand, India

Date of Submission31-Aug-2019
Date of Acceptance09-May-2020
Date of Web Publication09-Mar-2021

Correspondence Address:
Dr. Rituparna Dasgupta
Rims Girls' Hostel, RIMS, Bariatu, Ranchi - 834 009, Jharkhand
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njs.NJS_40_19

Rights and Permissions
  Abstract 


Schwannomas are the most common benign tumors of peripheral nerves but are rare in adults. They have an extremely slow rate of growth before the onset of symptoms such as pain, paresthesia, and tingling. Giant schwannomas of the extremities can significantly affect the quality of life. With a correct diagnosis, the tumor can be extirpated with preservation of nerve function and a very low risk of recurrence. A case of a symptomatic giant schwannoma on thenar eminence of the right hand in an adult male is discussed in this report.

Keywords: Neurilemmoma, schwannoma, space-occupying lesion in hand, thenar eminence


How to cite this article:
Dasgupta R, Kumar B. Giant schwannoma on thenar aspect of the hand: A rare case report. Niger J Surg 2021;27:75-7

How to cite this URL:
Dasgupta R, Kumar B. Giant schwannoma on thenar aspect of the hand: A rare case report. Niger J Surg [serial online] 2021 [cited 2021 Dec 4];27:75-7. Available from: https://www.nigerianjsurg.com/text.asp?2021/27/1/75/311013




  Introduction Top


Schwannoma or neurilemmoma is the most common type of peripheral nerve sheath tumor arising from Schwann cells,[1],[2] accounting for 5% of upper extremity tumors,[3] and is usually seen in the third to sixth decades of life. These benign, encapsulated, slow-growing tumors rarely transform into malignancy. Nearly 90% of these tumors are sporadic and the rest are associated with neurofibromatosis Type 1 and 2.[4] Differentials include ganglion cyst, giant cell tumor of tendon sheath, leiomyoma, neurofibroma, and carpal tunnel syndrome.[4],[5] Here, we report a case of symptomatic thenar eminence giant schwannoma of size 80 mm.


  Case Report Top


A 42-year-old male farmer from the rural outskirts of Ranchi, Jharkhand, presented to the general surgery outpatient department of our hospital with the complaint of a painless swelling in the right palm for the past 2 years [Figure 1]. The gradually increasing size of the swelling associated with numbness and tingling sensation in the right hand for 2 months before presentation prompted him to seek medical advice. The patient did not have any other complaints and could not recall any incident of trauma to the site of the swelling prior to its onset. There was no history of restriction of movement of the right wrist joint and fingers. He was a habitual tobacco chewer for 10 years. There was no history of such a presentation in any other family members.
Figure 1: Swelling on the thenar aspect of the right palm

Click here to view


On examination, a swelling of approximate size 5 cm × 3 cm was palpated in the thenar eminence of the right hand in between the first and second metacarpals, having smooth lobulated surface, well-defined margins, and soft consistency. The swelling was nontender, nonpulsatile, not fixed to the skin or underlying structures, and fluctuation was absent. It could not be compressed, and Tinel's sign was positive. There was no other similar swelling in the body. General examination of the patient was unremarkable.

Magnetic resonance imaging (MRI) of the hand and wrist revealed a well-defined, sharply demarcated, heterogeneously hyperintense lesion of size 6 cm × 3 cm on proton density and T2-weighted images and hypointense on T1-weighted seen along the thenar eminence of the right hand with widening of space between the first and second metacarpals suggestive of a space-occupying lesion (SOL) in the hand with a benign pathology [Figure 2]. Fine-needle aspiration cytology of the swelling was sought and reported inflammatory cells against a necrotic background.
Figure 2: Magnetic resonance imaging (T2-weighted) showing a well-defined, sharply demarcated, heterogeneously hyperintense lesion

Click here to view


On clinical and investigational grounds, total excision of the lesion was decided. Under regional anesthesia with wrist block using 2% lignocaine, a 3-cm-long incision was made 1 cm proximal to the thenar crease and extended to 5 cm on the dorsal surface in the first web space. After careful dissection and identification of the digital nerve and vessels, an 8.0 cm × 2.5 cm × 2.5 cm lobulated mass was seen to be arising from a digital nerve in the thenar eminence, which was excised in toto via blunt dissection [Figure 3]a and [Figure 3]b. The postoperative recovery was uneventful, and the patient was discharged from the hospital after 7 days of inpatient observation.
Figure 3: (a) Intraoperative view of the lesion while dissection. (b) Specimen after complete excision

Click here to view


Histopathological examination of the excised specimen revealed an encapsulated lesion consisting of spindle cells in alternating hypercellular (Antoni A) and myxoid hypocellular (Antoni B) areas. Focal nuclear regimentation with hyaline changes was seen with no evidence of malignancy suggestive of a neurilemmoma/schwannoma. Immunohistochemical study could not be performed because of its unavailability in our facility.

At 3rd-week follow-up visit, the patient seemed to have recovered well. The wound was healed properly, and there was no complaint of paresthesia or any evidence of recurrence [Figure 4].
Figure 4: Image of the right hand after 3 weeks of surgical excision of the space-occupying lesion

Click here to view



  Discussion Top


Schwannomas are rare tumors, and their preoperative diagnosis is often difficult.[6],[7],[8] A differential diagnosis of schwannoma must always be kept in mind when dealing with soft-tissue swellings in the extremities. These can be large swellings affecting the quality of life of the patient significantly. Long-standing cases may transform rarely into malignant peripheral nerve sheath tumor, angiosarcoma, or epithelioid malignancy.[4] Our patient sought medical advice owing to the tingling and numbness arising due to mass effect of the swelling. MRI and ultrasound (US) are useful investigations in such cases. Schwannomas are usually solitary tumors, which show low-intensity signals in T1-weighted and high-intensity signals in T2-weighted images.[9] They present as a lobulated, encapsulated, and highly vascularized mass on US. In our case, MRI could delineate a benign SOL amenable for surgical resection. The treatment of choice is total excision in which care should be taken not to damage the digital nerves and vessels. Schwannomas usually do not infiltrate the parent nerve and in our case, the tumor could be easily separated from the nerve. The most common postoperative complication is reported to be paresthesia,[5] which was never complained by our patient. The largest size of schwannoma of hand reported till date is of 3.1 cm × 5.1 cm.[5] A similar sized swelling was also reported by Sando et al. in an infant.[10] The present case is probably of the largest sized schwannoma of hand reported till date, which was completely cured by surgical intervention.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Loius DS, Hankin FM. Benign nerve tumours of upper extremity. Bull NY Acad Med 1985;61:611-20.  Back to cited text no. 1
    
2.
Harkin JC, Reed RS. Tumours of peripheral nervous system. In: Atlas of Tumour Pathology. Washington DC: Armed Forces Institute of Pathology; 1969. p. 110-6.  Back to cited text no. 2
    
3.
Adani R, Baccarani A, Guidi E, Tarallo L. Schwannomas of the upper extremity: Diagnosis and treatment. Chir Organi Mov 2008;92:85-8.  Back to cited text no. 3
    
4.
Schwannoma AE. PathologyOutlines.com website. Available from: http://www.pathologyoutlines.com/topic/so fttissueschwannoma.html. [Last accessed on 2019 Jul 28].  Back to cited text no. 4
    
5.
Turkkan S, Coskun E, Tuzun HY, Arsenishvili A, Can N, Cicek AF, et al. Schwannoma on palmar surface of the hand: A rare case report. Hand Microsurg 2015;4:71-4.  Back to cited text no. 5
    
6.
Whitaker WG, Droulias C. Benign encapsulated neurilemoma: A report of 76 cases. Am Surg 1976;42:675-8.  Back to cited text no. 6
    
7.
Holdsworth BJ. Nerve tumours in the upper limb. A clinical review. J Hand Surg Br 1985;10:236-8.  Back to cited text no. 7
    
8.
White NB. Neurilemmomas of the extremities. J Bone Joint Surg Am 1967;49:1605-10.  Back to cited text no. 8
    
9.
Kuo YL, Chiu HY, Yao WJ, Shieh SJ. Ultrasound for schwannoma in the upper extremity. J Hand Surg Eur Vol 2009;34:697-8.  Back to cited text no. 9
    
10.
Sando IC, Ono S, Chung KC. Schwannoma of the hand in an infant: Case report. J Hand Surg Am 2012;37:2007-11.  Back to cited text no. 10
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

Top
   
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
Abstract
Introduction
Case Report
Discussion
References
Article Figures

 Article Access Statistics
    Viewed545    
    Printed8    
    Emailed0    
    PDF Downloaded39    
    Comments [Add]    

Recommend this journal